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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A16
All Species:
22.42
Human Site:
Y35
Identified Species:
32.89
UniProt:
P16260
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16260
NP_689920.1
332
36224
Y35
P
T
T
R
R
D
F
Y
W
L
R
S
F
L
A
Chimpanzee
Pan troglodytes
XP_001168284
332
36249
Y35
P
T
T
R
R
D
F
Y
W
L
R
S
F
L
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546134
332
36141
Y35
P
A
A
R
R
D
F
Y
W
L
R
S
F
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0K5
332
36201
Y35
P
T
S
R
R
D
F
Y
W
L
R
S
F
L
A
Rat
Rattus norvegicus
P16261
322
35038
Y35
P
T
S
R
R
D
F
Y
W
L
R
S
F
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520566
324
35638
S27
L
W
N
S
E
C
N
S
F
P
F
L
S
L
S
Chicken
Gallus gallus
XP_421570
320
35184
R26
R
R
D
F
Y
W
L
R
S
F
I
A
G
G
V
Frog
Xenopus laevis
Q5PQ27
327
36043
S35
E
G
H
K
N
H
K
S
V
L
N
S
L
T
S
Zebra Danio
Brachydanio rerio
Q0P483
321
35318
S26
P
R
P
A
A
S
Q
S
E
G
F
K
Q
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624199
316
35726
M26
I
A
G
G
V
A
G
M
C
S
K
T
T
V
A
Nematode Worm
Caenorhab. elegans
Q20799
588
66319
I247
Q
Q
E
M
Q
E
G
I
W
W
R
H
L
V
A
Sea Urchin
Strong. purpuratus
XP_789697
271
30376
Poplar Tree
Populus trichocarpa
XP_002308549
340
37252
V34
S
L
L
D
D
V
P
V
Y
V
K
E
L
I
A
Maize
Zea mays
P29518
436
46609
P133
G
Q
G
Q
D
R
Q
P
A
P
A
R
L
V
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172908
331
36237
T26
T
L
P
V
L
A
K
T
L
I
A
G
G
A
A
Baker's Yeast
Sacchar. cerevisiae
P38702
357
40807
Y32
F
D
R
N
S
F
D
Y
I
V
R
S
G
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
96
N.A.
92.7
88.8
N.A.
82.5
81
37
38.2
N.A.
N.A.
50.2
20.2
39.7
Protein Similarity:
100
99.6
N.A.
98.1
N.A.
96.6
92.7
N.A.
87.9
86.7
54.2
53.9
N.A.
N.A.
62
31.6
53.6
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
93.3
N.A.
6.6
0
13.3
6.6
N.A.
N.A.
6.6
20
0
P-Site Similarity:
100
100
N.A.
86.6
N.A.
100
100
N.A.
20
6.6
26.6
6.6
N.A.
N.A.
26.6
40
0
Percent
Protein Identity:
34.4
21.7
N.A.
37.9
37.5
N.A.
Protein Similarity:
54.4
34.8
N.A.
53.6
55.1
N.A.
P-Site Identity:
6.6
0
N.A.
6.6
33.3
N.A.
P-Site Similarity:
33.3
20
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
7
7
7
13
0
0
7
0
13
7
0
7
63
% A
% Cys:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
7
7
13
32
7
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
7
0
7
7
0
0
7
0
0
7
0
0
0
% E
% Phe:
7
0
0
7
0
7
32
0
7
7
13
0
32
0
0
% F
% Gly:
7
7
13
7
0
0
13
0
0
7
0
7
19
13
0
% G
% His:
0
0
7
0
0
7
0
0
0
0
0
7
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
7
7
7
7
0
0
7
0
% I
% Lys:
0
0
0
7
0
0
13
0
0
0
13
7
0
0
0
% K
% Leu:
7
13
7
0
7
0
7
0
7
38
0
7
25
44
0
% L
% Met:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
7
0
7
0
0
0
7
0
0
0
0
% N
% Pro:
38
0
13
0
0
0
7
7
0
13
0
0
0
0
0
% P
% Gln:
7
13
0
7
7
0
13
0
0
0
0
0
7
0
0
% Q
% Arg:
7
13
7
32
32
7
0
7
0
0
44
7
0
0
7
% R
% Ser:
7
0
13
7
7
7
0
19
7
7
0
44
7
0
19
% S
% Thr:
7
25
13
0
0
0
0
7
0
0
0
7
7
7
0
% T
% Val:
0
0
0
7
7
7
0
7
7
13
0
0
0
19
7
% V
% Trp:
0
7
0
0
0
7
0
0
38
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
38
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _